Amitriptyline and Benadryl

[squid13]

Does anyone take small douses of Amitriptyline and Benadryl at Bedtime? If so how does it work?

[chunkyfrog]

Not I.
I just mask up, lie down, and conk out.

[Madalot]

I take Benedryl at bedtime to help me stay asleep. For me, it works reasonably well.

Are you asking for people that take both medications? I can only give you my experience with the one of the two you mentioned.

[squid13]

I'm asking if anyone takes both. I' love to lie down and conk out but I wake 3 to 4 times a night so my sleep is fractured. I take 20 MG of Amitriptyline and it helps with my aches and pains but it doesn't keep me asleep so I thought if I took some Benadrly it might work.

[Madalot]

Gotcha! I take at bedtime, in addition to the benedryl:

Gabapentin
Tramadol
Advil

My pain is controlled with the above meds but the benedryl was needed because I was waking up anywhere from 4-10 times a night. I still wake up, but not quite as often and not as fully, so going back to sleep IS easier.

I hope you can get some input about your specific medication questions.

[msradar65]

Ihave used Amitriptyline for sleep. I started at 25mg and the doctor increased it to 50mg because I was having night terrors when I first started CPAP. I rarely take it now.

[Pugsy]

http://reference.medscape.com/drug-interactionchecker

both cause drowsiness...we knew that.
something about cholinergic which I don't understand

Says to monitor closely. In the small doses that you would be taking I probably wouldn't be afraid to take it.
I currently take a combination that has a much stronger warning than "monitor closely".
Best thing of course is to ask doctor for final say so.

Benadryl and men with enlarged prostrate might be a problem...just thought I would bring that up.

[BlackSpinner]

Benadryl, though it makes me sleepy and fall asleep, wakes me up and makes me very restless for the rest of the night.

[LSAT]

10mg of amitriptyline knocks me out for 8 hours....I only use it occasionally

[W7SOT]

have any of you noticed any major changes in your number when you take the amytriptylyne? I take 75MG, and I noticed that my AHI went WAY up, and the next day, I felt like I didn't get any sleep the night before

[Pugsy]

have any of you noticed any major changes in your number when you take the amytriptylyne? I take 75MG, and I noticed that my AHI went WAY up, and the next day, I felt like I didn't get any sleep the night before

I haven't seen any difference in numbers at all but then I only take a small dose 25 mg at bedtime.
No particular pattern that is obvious with or without meds.

If you really think it is the meds then don't take it for a week...monitor data...then take it for a week and compare.
Need more than a night or two though to establish a pattern.

[squid13]

I only take 20 mg at bedtime and I take it for pain relief so if it did go up a little I wouldn't stop it cause the benefit is worth a little jump in AHI. So far though I haven't seen any rise in AHI. Making you sleepy is just a nice side effect.

[DannyPh]

I take a dose of Nyquil nightly as a sleep aide and helps with nasal congestion too.

[Jay Aitchsee]

http://www.medscape.org/viewarticle/495339